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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP9
All Species:
10.61
Human Site:
S133
Identified Species:
19.44
UniProt:
P55211
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55211
NP_001220.2
416
46281
S133
P
R
P
V
D
I
G
S
G
G
F
G
D
V
G
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
S26
K
I
I
H
G
S
Q
S
M
D
S
G
I
S
L
Rhesus Macaque
Macaca mulatta
XP_001082859
416
46192
S133
P
R
P
V
D
I
G
S
G
G
C
G
D
V
G
Dog
Lupus familis
XP_865164
414
45235
S132
P
R
P
T
D
N
G
S
G
R
F
S
D
V
C
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
P172
L
D
N
G
D
G
P
P
C
L
L
V
K
P
C
Rat
Rattus norvegicus
P55215
452
50709
P172
L
D
N
G
D
G
P
P
C
L
Q
V
K
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520982
366
40213
S107
I
K
V
Y
S
L
K
S
E
P
C
G
H
C
L
Chicken
Gallus gallus
Q98943
424
47941
P143
L
D
S
G
D
G
P
P
I
P
P
V
K
H
C
Frog
Xenopus laevis
P55866
282
32106
C31
Q
P
R
S
L
Q
N
C
D
L
K
D
I
E
R
Zebra Danio
Brachydanio rerio
NP_001007405
436
48445
S144
L
P
V
H
K
T
Y
S
P
P
S
E
T
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
E70
P
V
E
R
Y
A
S
E
Y
N
M
S
H
K
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
A149
Y
Q
D
I
Y
S
R
A
R
S
R
S
R
S
R
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
S137
D
S
T
G
D
Y
S
S
T
Q
M
D
A
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
93.9
76.9
N.A.
28.9
28.3
N.A.
52.8
31.1
22.6
47.2
N.A.
22.1
N.A.
21.6
32.2
Protein Similarity:
100
35.8
96.8
84.1
N.A.
46.9
46.2
N.A.
65.6
48.3
38.7
64.2
N.A.
35.8
N.A.
37.5
51
P-Site Identity:
100
13.3
93.3
66.6
N.A.
6.6
6.6
N.A.
13.3
6.6
0
13.3
N.A.
6.6
N.A.
0
20
P-Site Similarity:
100
13.3
93.3
66.6
N.A.
6.6
6.6
N.A.
26.6
6.6
0
13.3
N.A.
6.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
16
0
16
0
0
8
31
% C
% Asp:
8
24
8
0
54
0
0
0
8
8
0
16
24
0
0
% D
% Glu:
0
0
8
0
0
0
0
8
8
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% F
% Gly:
0
0
0
31
8
24
24
0
24
16
0
31
0
0
24
% G
% His:
0
0
0
16
0
0
0
0
0
0
0
0
16
8
8
% H
% Ile:
8
8
8
8
0
16
0
0
8
0
0
0
16
0
0
% I
% Lys:
8
8
0
0
8
0
8
0
0
0
8
0
24
8
0
% K
% Leu:
31
0
0
0
8
8
0
0
0
24
8
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
8
0
16
0
0
0
0
% M
% Asn:
0
0
16
0
0
8
8
0
0
8
0
0
0
0
0
% N
% Pro:
31
16
24
0
0
0
24
24
8
24
8
0
0
16
0
% P
% Gln:
8
8
0
0
0
8
8
0
0
8
8
0
0
0
0
% Q
% Arg:
0
24
8
8
0
0
8
0
8
8
8
0
8
0
16
% R
% Ser:
0
8
8
8
8
16
16
54
0
8
16
24
0
24
0
% S
% Thr:
0
0
8
8
0
8
0
0
8
0
0
0
8
0
0
% T
% Val:
0
8
16
16
0
0
0
0
0
0
0
24
0
31
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
16
8
8
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _